RICERCA ITALIANA     

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Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • GENETICA MEDICA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • DIAGNOSIS; SURGERY; IDENTIFICATION (analysing biological material G01N, e.g. G01N33/48; obtaining records using waves other than optical waves, in general G03B42/00)

Classificazione geografica

• Regione: Puglia

Bibliografia

1. Schena FP. A retrospective analysis of the natural history of primary IgA nephropathy wordwide. Am J Med 89: 209-215, 1990
2. Schena FP. IgA nephropathies. In: A.M. Davison et al (eds): Oxford Textbook of Clinical Nephrology, Oxford University Press, Oxford, U.K., pp. 537-570, 1997
3. D’Altri C, Manno C, Rossini M, Cerullo G, Schena FP. Studio clinico-patologico restrospettivo in 543 pazienti affetti da nefropatia IgA. Giornale Italiano di Nefrologia 18:425-432;2001
4. Valderrabano F, Berthoux FC, Jones EHP, Mehls O, of the EDTA-ERA Registry. Report on management of renal failure in Europe, XXV, 1994. End stage renal disease and dialysis report. Nephrol Dial Transplant 11:2-21, 1996
5. www.health-tech-net.org/irrb
6. Schena FP and The Italian Group of Renal Immunopathology: Survey of the Italian registry of renal biopsies. Frequency of the renal disease for 7 consecutive years. Nephrol Dial Transplant 12: 418-426; 1997
7. Tolkoff-Rubin NE, Cosimi BA, Fuller T, Rubin RH, Colvin RB. igA nephropathy in HLA-identical siblings. Transplantation 26:430-433, 1978
8. Scolari F. Familial IgA nephropathy. J Nephrol 12: 213-219, 1999
9. Egido J, Garcia-Hoyo R, Lozano L, Gonzales-Cabrero J, de Nicolas R, Hernando L. Immunological studies in familial and sporadic IgA nephropathy. Sem Nephrol 7: 311-314, 1987
10. Schena FP, Cerullo G, Rossini M, Lanzilotta SG, D’Altri C, Manno C. Increased risk of end stage renal disease in familial IgA nephropathy. J Am Soc Nephrol 12:2001(in press)
11. Schena F.P. Immunogenetic aspects of primary IgA nephropathy-Nephrology Forum. Kidney Int 48: 1998-2013, 1995
12. Scolari F, Amoroso A, Savoldi S, Prati E, Scaini P, Manganoni A, Borelli I, Mazzola G, Canale L, Sacchi G, Miglietti N, Cristinelli L, Curtoni ES, Binda PL, Bonomelli D, Maiorca R. Familial occurence of primary glomerulonephritis: evidence for a role of genetic factors. Nephrol Dial Transplant 7: 587-596, 1992
13. Scolari F, Amoroso A, Savoldi S, Mazzola G, Prati E, Valzorio B, Viola BF, Bossini N, Movilli E, Sandrini M, Campanini M, Maiorca R. Familial clustering of IgA nephropathy: further evidence in an Italian population. Am J Kidney Dis 33: 857-865, 1999
14. Gharavi AG, Yan Y, Scolari F, Schena FP, Frascà GM, Ghiggeri GM et al. IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23. Nature Genet 26: 354-357, 2000
15. Levy M. Cas familiaux de maladie de Berger ou de maladie de Berger et de purpura rhumatoïde. Etude coopérative de la Société Francaise de Néphrologie. Nephrologie 10, 175-182, 1989
16.Cosio FG, Falkenhain ME, Sedmak DD.Association of thin glomerular basement membrane with other glomerulopathies.Kidney Int.46:471-474,1994
17.Frascà GM, Onetti-Muda A, Renieri A. Thin glomerular basement membrane disease.J.Nephrol. 13:15-19, 2000
18. Schena FP, Scivittaro V, Ranieri E, Sinico R, Benuzzi S, Di Cillo M, Aventaggiato L. Abnormalities of the IgA immune system in members of unrelated pedigrees from patients with IgA nephropathy. Clin Exp Immunol 92: 139-144, 1993
19. Scivittaro V, Gesualdo L, Ranieri E, Marfella C, Schewn SA, Emancipator SN, Schena FP. Profiles of immunoregulatory cytokine production in vitro in patients with IgA nephropathy and their kindred. Clin Exp Immunol 96: 311-316, 1994
20. Scivittaro V, Ranieri E, Di Cillo M, Aventaggiato L, Emancipator SN, Schena FP. In vitro immunoglobulin production in relatives of patients with IgA nephropathy. Clin Nephrol 42: 1-8, 1994
21.I-Hong Hsu S, Ramirez SB, Winn MP, Bonventre JV, Owen WF.Kidney Int.57:1818-1835, 2000
22. Pirulli D, Boniotto M, Vatta L, Crovella S, Spanò A, Puzzer D, Zezlina S, Bertola L, Roccatello D, Scolari F, Peruzzi L, Amoroso A. Polymorphisms of the promoter and of the codon 54 in the MBL2 gene are not associated with IgA nephropathy. Nephrol Dial Transplant.16:759-764, 2001
23. Schena FP, D’Altri C, Cerullo G, Manno C, Gesualdo L. ACE genepolymorphism and IgA nephropathy. An ethnically homogeneous study and a meta-analysis review. Kidney Int 60: 732-740, 2001
24. Suzuki S, Suzuki Y, Kobayashi Y, Harada T, Kawamura T, Yoshida H, and Tomino Y. Am J Kidney Dis 35: 896-903, 2000
25. Gambaro G. Anglani F, D’Angelo A. Association studies of genetic polymorphisms and complex disease. Lancet 355: 308-311, 2000
26.Schena FP, Pastore A, Sinico RA, Montinaro V, Fornasieri A. Polymeric IgA and IgA rhematoid factor decrease the capacity of serum to solubilize circulating immune complexes in patients with primary IgA nephropaty. J Immunol.141:125-130,1988
27.Hiki Y, Odani H, Takahashi M, Yasuda Y, Nishimoto A, Iwase H, Shinzato T, Kobayashi Y, Maeda K. Kidney Int.59;1077-1085,2001
28.Schena FP, Pastore A, Ludovico N, Sinico RA, Benuzzi S, Montinaro V.Increased serum levels of IgA1-IgG immune complexes and anti-F(ab')2 antibodies in patients with primary IgA nephropathy.Clin.Exp.Immunol.77:15-20,1989
29.Staudt LM.Gene expression physiology and pathophysiology of the immune system. Trends in Immunology.22:35-40,2001
30.Alizadeh AA. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature.403:503-511,2000
31.Churg J, Sobin L.H. In Renal disease. Classification and atlas of glomerular disease. Igaku-Shoin, Tokyo, New York, 1982
32.Duque N, Gomez-Guerrero C, Egido J. Interaction of IgA with Fc alfa Receptors of human mesangial cells activates transcription factor nuclear factor-kB and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8 and IFN-inducible protein 10. J.Immunol.159:3474-3482;1997
33.Rifai A, Schena FP, Montinaro V, Mele M, D'Addabbo A, Nitti L, Pezzullo JC.Clearance kinetics and fate of macromolecular IgA in patients with IgA nephropathy.Lab Invest.61:381-388.1989
34. Szeto CC, Lai F MM, To KF, Wong TYH, Chow KM, Choi PCL, Lui SF, Li PKT. Natural history of IgA nephropathy presenting with hematuria and minimal proteinuria. Am J Med. 110:434-437, 2001
35. Schena FP. IgA nephropathy with mild renal lesions. A call in the forest for physicians and nephrologists. Am J Med.110:499-500. 2001
36.Gesualdo L, Di Paolo S, Milani S, Pinzani M, Grappone C, Ranieri E, Pannarale G, Schena FP.Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study.J Clin Invest. 94:50-58, 1994
37.Grandaliano G, Gesualdo L, Ranieri E, Monno R, Montinaro V, Marra F, Schena FP.Monocyte chemotactic peptide-1 expression in acute and chronic human nephritides: a pathogenetic role in interstitial monocytes recruitment.J Am Soc Nephrol. 7:906-913, 1996

Parole Chiave

IgA nefropatia; Analisi di Linkage; Malattie renali; Genomica; Proteomica; Microarray