RICERCA ITALIANA     

FIRB simili:

• 1 - Misfolding di proteine e patologie umane: studio della conversione patologica di proteine globulari in aggregati fibrillari e sviluppo di farmaci che inibiscano i processi di misfolding e aggregazione
• 2 - MALATTIE NEURODEGENERATIVE COME CONSEGUENZA DI UN ALTERATO PROCESSAMENTO DI PROTEINE NEURONALI. MODELLI ANIMALI E DI COLTURE CELLULARI IN VITRO.
• 3 - Meccanismi molecolari della morte cellulare e loro implicazione in patologia umana
• 4 - Interazioni funzionali tra proteine delle sinapsi: fisiopatologia e potenziali indicazioni terapeutiche
• 5 - FOLDING E AGGREGAZIONE DI PROTEINE: METALLI E BIOMOLECOLE NELLE MALATTIE CONFORMAZIONALI
• 6 - Riconoscimento molecolare e funzionalità cellulare
• 7 - Sviluppo di Tecnologie Avanzate per lo Studio della Proteomica Differenziale del Segnale (Segnalo-Proteomica)
• 8 - Il riconoscimento molecolare nelle interazioni proteina-ligando, proteina-proteina e proteina superficie: sviluppo di approcci sperimentali e computazionali integrati per lo studio di sistemi di interesse farmaceutico
• 9 - PROTEASI NELLA RISPOSTA CELLULARE NORMALE E PATOLOGICA: IDENTIFICAZIONE DEI SUBSTRATI ENDOGENI E DEI MECCANISMI MOLECOLARI INDOTTI
• 10 - Metabolismo e organizzazione degli sfingolipidi in modelli di neurodegenerazione cellulare: comprensione dei meccanismi molecolari di base e sviluppo di nuove strategie terapeutiche.

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze biologiche
  • BIOCHIMICA
  • FARMACOLOGIA
• Area scientifico disciplinare: Scienze mediche
  • PATOLOGIA GENERALE

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)
  • ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B3/00, C25B7/00)
    • PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)

Classificazione geografica

• Regione: Sicilia

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Parole Chiave

farmaci antiossidanti; farmaci antifibrillogenici; inibitori delle secretasi; chemiochine; malattie conformazionali; glia