RICERCA ITALIANA     

FIRB simili:

• 1 - L'ingegneria dei tessuti per la rigenerazione dei tessuti connettivi con particolare riferimento al tessuto osseo
• 2 - Cellule staminali adulte pluripotenti per la ricostituzione tissutale in modelli di malattie degenerative
• 3 - BILANCIO OSPITE-TUMORE NELLA TERAPIA MEDICA DELLE NEOPLASIE: RUOLO DI NF-kB
• 4 - Meccanismi molecolari della morte cellulare e loro implicazione in patologia umana
• 5 - Identificazione, purificazione, transdifferenziazione e banking di cellule staminali indirizzate verso fenotipi propri e non propri da utilizzare per riparazione tissutale
• 6 - ANALISI FUNZIONALE DI GENI PATOLOGICI IMPLICATI NEL MANTENIMENTO DELL'INTEGRITÀ DEL GENOMA
• 7 - Approcci combinati di terapia genica nel trattamento del glioblastoma
• 8 - Studio dell'identità cellulare e dei meccanismi di differenziazione cellulare nell'era della postegnomica utilizzando tre situazioni paradigmatiche: la mammella, l'osso e i linfociti
• 9 - Modulazione razionale dell'attività antitumorale di farmaci "classici" tramite intervento selettivo su specifiche cascate regolatorie
• 10 - www*.neuralstemcells.it (*where,when,why)

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • PATOLOGIA GENERALE
  • ANATOMIA PATOLOGICA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (bringing into special physical form A61J [N: mechanical aspects]; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; compounds per se C01, C07, C08, C12N; soap compositions C11D; micro-organisms per se C12N) [C0203]

Classificazione geografica

• Regione: Lazio

Bibliografia

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New Engl J Med, 345:24-32, 2001
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- Guttridge DC, Mayo MW, Madrid LW, Wang CY, Baldwin AS: NFkB-induced loss of MyoD mRNA: possible role in muscle decay and cachexia. Science, 289:2293-2294, 2000.
- Izumo S, Lompre AM, Matsuoka R, Koren G, Schwartz K, Nadal-Ginard B, Mahdavi V. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. J Clin Invest. 1987 Mar;79(3):970-7.
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- Kajstura J, Fiordaliso F, Andreoli AM, Li B, Chimenti S, Medow MS, Limana F, Nadal-Ginard B, Leri A and Anversa P: IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II- mediated oxidative stress. Diabetes 50(6): 1414-1424, 2001.
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- Perry VH, Anthony DC. Axon damage and repair in multiple sclerosis. Philos Trans R Soc Lond B Biol Sci, 354(1390):1641-7, 1999.
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- Sakai T, Johnson KJ, Murozono M, Sakai K, Magnuson MA, Wieloch T, Cronberg T, Isshiki A, Erickson HP, Fassler R. Plasm fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat Med, 7(3):324-30, 2001.
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- Thaloor D, Miller KJ, Gephart J, Mitchell PO, Pavlath GK: Systemic administration of the NFkB inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol, 277:C320-329, 1999.
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- Yamashit K, Kajstura J ,Discher DJ, Wasserlauf BJ, Bishopric NH, Anversa P, Webster KA: Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse heart overexpressing Insulin-like Growth Factor-1. Circ Res, 88:609-614, 2001.
- Zhu YZ, Chimon GN, Zhu YC, Lu Q, Li B, Hu HZ, Yap EH, Lee HS, Wong PT. Expression of angiotensin II AT2 receptor in the acute phase of stroke in rats. Neuroreport 11(6):1191-4, 2000.

Parole Chiave

Riparazione molecolare; Scompenso miocardico; Miopatie scheletriche degenerative; Malattie nuerodegenerative; Signalling riparativo; DNA microarrays della riparazione