RICERCA ITALIANA     

FIRB simili:

• 1 - Bioinformatica per la Genomica e la Proteomica
• 2 - PIATTAFORME ABILITANTI PER GRIGLIE COMPUTAZIONALI A ELEVATE PRESTAZIONI ORIENTATE A ORGANIZZAZIONI VIRTUALI SCALABILI
• 3 - Sistemi di diagnostica molecolare per l'identificazione e l'analisi di determinanti genetici di rilevanza per l'agroindustria, la zootecnica e l'ambiente
• 4 - Sviluppo di microsistemi multifunzionali per analisi in diagnostica clinica e nel settore alimentare
• 5 - Manipolazione di biomolecole, fluidi, sistemi e dati per la tecnologia Bio-chip
• 6 - VIRTUAL IMMERSIVE COMMUNICATIONS (VICOM)
• 7 - Microtecnologie per la telepresenza immersiva virtuale
• 8 - Sviluppo di metodologie innovative per l'identificazione e la sintesi di nuove molecole a scopo terapeutico: applicazioni nel campo della malattia di Alzheimer
• 9 - NANOTECNOLOGIE E NANOSCIENZE ORGANICHE

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze fisiche
  • FISICA SPERIMENTALE
• Area scientifico disciplinare: Ingegneria industriale e dell'informazione
  • SISTEMI DI ELABORAZIONE DELLE INFORMAZIONI

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)

Classificazione geografica

• Regione: Lazio

Bibliografia

 Tavladoraki P., Benvenuto E., Trinca S., De Martinis D., Cattaneo A., Galeffi P. (1993). Transgenic plants expressing a functional "Single Chain Fv" antibody are specifically protected from virus attack. Nature 366: 469-472.
 Benvenuto E., Tavladoraki P. (1995). Immunotherapy of plant viral diseases. Trends in Microbiology 3 : 272-275.
 Tavladoraki P., Girotti A., Donini M., Arias F.J., Mancini C., Morea V., Chiaraluce R., Consalvi V., Benvenuto E. (1999). A single-chain antibody fragment is functionally expressed in the cytoplasm of both Escherichia coli and transgenic plants. European Journal Biochemistry 262: 617-24.
 Franconi R., Roggero P., Pirazzi P., Arias F.J., Desiderio A., Bitti O., Pashkoulov D., Mattei B., Bracci L., Masenga V., Milne R.G., Benvenuto E. (1999). Functional expression in bacteria and plants of an scFv antibody fragment against tospoviruses. Immunotechnology 4: 189-201.
 Roggero P., Ciuffo M., Benvenuto E., Franconi R. (2001). 'The expression of a single-chain Fv antibody fragment in different plant hosts and tissues by using potato virus X as a vector'. Protein Expression and Purification 22: 70-74.
 Marusic C., Rizza P., Lattanzi L., Mancini C., Spada M., Belardelli F., Benvenuto E., Capone I. (2001). Chimeric Plant Virus Particles as Immunogens for Inducing Murine and Human Immune Responses against Human Immunodeficiency Virus Type 1. Journal of Virology 75: 8434-8439.
 Desiderio A., Franconi R., Lopez M., Villani M. E., Chiaraluce R., Consalvi V., Neri D., Benvenuto E. (2001). A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold. Journal of Molecular Biology 310: 603-615.
 Dolezel, J., Greilhuber, J., Lucretti, S., Meister, A., LysaK, M.A., Nardi, L., Obermayer, R. (1998). Plant genome size estimation by flow cytometry: inter-laboratory comparison. Ann. Bot. 82, Suppl. A: 17-26.
 Barcaccia G., Mazzucato A., Belardinelli A., Pezzotti M., Lucretti S., Falcinelli M. (1997) “Inheritance of parental genomes in progenies of Poa pratensis L. from sexual and apomictic genotypes as assessed by RAPD markers and flow cytometry” Theor. Appl. Gen. 95:516-524.
 Bartley G., Scolnik P.A. and Giuliano G. (1994) Molecular biology of carotenoid biosynthesis in plants. Ann Rev Plant Physiol Plant Mol Biol 45, 287-301.
 Weller J.L., Perrotta G., Schreuder M.E., van Tuinen A., Koornnef M., Giuliano G. Kendrick R.E. (2001). Genetic dissection of blue-light sensing in tomato using mutants deficient in cryptochrome 1 and phytochromes A, B1 and B2. Plant J. 25:427-440
 Rosati C., Aquilani R., Dharmapuri S., Pallara P., Marusic C., Tavazza R., Bouvier F., Camara B., Giuliano G., (2000). Metabolic engineering of beta-carotene and lycopene content in tomato fruit. Plant J. 24: 413-419.
 Ninu L., Ahmad M., Miarelli C., Cashmore A.R., Giuliano G. (1999). Cryptochrome 1 controls tomato development in response to blue light. Plant J. 18: 551-556.
 Giuliano G., Aquilani R., Dharmapuri S. (2000). Metabolic engineering of plant carotenoids. Trends Plant Sci. 5: 406-409.
 von Lintig J., Welsch R., Bonk M., Giuliano G., Batschauer A., Kleinig H., (1997). Light-dependent regulation of carotenoid biosynthesis occurs at the level of phytoene synthase expression and is mediated by phytochrome in Sinapis alba and Arabidopsis thaliana seedlings. Plant J. 12: 625-634.
 Fiore A., Laevens S., Bevivino A., Dalmastri C., Tabacchioni S., Vandamme P., Chiarini L., (2001). Burkholderia cepacia complex: distribution of genomovars among isolates from the maize rhizosphere in Italy. Environ Microbiol. 3: 137-143.
 Chiarini L., Giovanelli V., Bevivino A., Dalmastri C., Tabacchioni S., (2000). Different portions of the maize root system host Burkholderia cepacia populations with different degrees of genetic polymorphism.
Environ Microbiol. 2: 111-118.
 Tabacchioni S., Chiarini L., Bevivino A., Cantale C., Dalmastri C., (2000). Bias Caused by Using Different Isolation Media for Assessing the Genetic Diversity of a Natural Microbial Population. Microb Ecol. 40: 169-176.
 Dalmastri C., Chiarini L., Cantale C., Bevivino A., Tabacchioni S., (1999). Soil Type and Maize Cultivar Affect the Genetic Diversity of Maize Root-Associated Burkholderia cepacia Populations. Microb Ecol. 38: 273-284.
 Noris E., Accotto G.P., Tavazza R., Brunetti A., Crespi S. and Tavazza M. (1996) Resistance to tomato yellow leaf curl geminivirus in Nicotiana benthamiana plants transformed with a truncated viral C1 gene. Virology 224, 130-138.
 Brunetti A., Tavazza M., Noris E., Tavazza R., Caciagli P., Ancora G., Crespi S., and Accotto G.P. (1997) High expression of truncated viral rep protein cofers resistance to tomato yellow leaf curl virus in transgenic tomato plants. Molecular Plant Microbe-Interaction 10, 571-579.
 Molinari P., Marusic C., Lucioli A., Tavazza R. and Tavazza M. (1998) Identification of artichoke mottled crinkle virus (AMCV) proteins required for virus replication: complementation of AMCV p33 and p92 replication-defective mutants. Journal of General Virology 79, 639-647.
 Bruneti A. , Tavazza R., Noris E., Lucioli A., Accotto G.P. and Tavazza M.. (2001). Transgenically expressed T-Rep of tomato yellow leaf curl Sardinia virus act as a trans-dominant negative mutant inhibiting viral transcription and replication. Journal of Virology in press.

BREVETTI
 Benvenuto E., Franconi R., Desiderio A., Tavladoraki P. Stabilizing peptides, polypeptides and antibodies which include them.(2000) EPO 00204725.6 e PCT/IT00/00554,
 Franconi R., Benvenuto E., Roggero P. Anticorpo a Singola Catena (scFv) contro i Tospovirus e Suo Uso in Diagnosi e Terapia in Piante.(1998) RM98A000526.
A. Belardelli F., Benvenuto E., Capone I., Marusic C., Rizza P., Proteina di fusione, particelle virali chimeriche che la espongono sul capside, piante infettate con tali particelle, loro usi e composizioni che li comprendono. EPO 01202225.7.
A. Franconi R, Giorgi C., Venuti A., Marcante M. L., Accardi L., Di Bonito P., Dibello F., Bitti O.
'Vaccini a subunità e procedimenti per la loro produzione'. (2001) RM2001A000332.

Parole Chiave

genomica; proteomica; bioinformatica; sequenziamento; modellazione molecolare; Anticorpi ingegnerizzati