RICERCA ITALIANA     

FIRB simili:

• 1 - Approcci combinati di terapia genica nel trattamento del glioblastoma
• 2 - Sviluppo di biotecnologie e di sistemi per il miglioramento della cura e del monitoraggio di tumori solidi mediante perfusione locoregionale
• 3 - Molecole innovative ad attività antiflogistica ed antitumorale prodotte con metodologie chimiche avanzate
• 4 - Il sistema di trasduzione del segnale Ca2+: dalle molecole alle funzioni
• 5 - BILANCIO OSPITE-TUMORE NELLA TERAPIA MEDICA DELLE NEOPLASIE: RUOLO DI NF-kB
• 6 - Riconoscimento molecolare e funzionalità cellulare
• 7 - Meccanismi di regolazione dello sviluppo del sistema nervoso e del differenziamento neurale (PRONEURO)
• 8 - Studio dell'identità cellulare e dei meccanismi di differenziazione cellulare nell'era della postegnomica utilizzando tre situazioni paradigmatiche: la mammella, l'osso e i linfociti
• 9 - Meccanismi molecolari della morte cellulare e loro implicazione in patologia umana
• 10 - Studio di microsistemi multifunzionali per determinazioni chimiche e biochimiche in matrici biologiche complesse

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze chimiche
  • CHIMICA ORGANICA
• Area scientifico disciplinare: Scienze mediche
  • DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B3/00, C25B7/00)
    • PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • DIAGNOSIS; SURGERY; IDENTIFICATION (analysing biological material G01N, e.g. G01N33/48; obtaining records using waves other than optical waves, in general G03B42/00)

Classificazione geografica

• Regione: Piemonte

Bibliografia

[1]P.A. Rinck, Magnetic Resonance in Medicine, Blackwell Scientific Publications, Oxford, 1993.
[2]S. Aime, M. Botta, M. Fasano, E. Terreno, Chem. Soc. Rev. 1998, 27, 19-29.
[3]P. Caravan, J.J. Ellison, T.J. McCurry, R.B. Lauffer, Chem. Soc. Rev. 1999, 99, 2293-2352.
[4]M.F. Tweedle, Invest. Radiol., 1992, 27, 2-6.
[5]J.A. Peters, J. Huskens, D.J. Raber, Prog. Nucl. Magn. Reson. Spectr., 1996, 28, 283-350.
[6]M. F. Tweedle, Lanthanide probes in life, Chemical and earth sciences, Theory and practise, Ed Bunzil C. G.e Choppin G. R.
[7]Chang, C. A., Eur. J. Solid State Inorg. Chem., 1991, 28, 237-244
[8]R.N. Muller, P. Gillis, F. Moiny ed al., Magn. Reson. Med., 1991, 22, 178-182.
[9]J. Platzek, P. Blaszkiewicz, H. Gries, P. Luger, G. Michl, A. Mueller-Fahrnow, B. Raduechel, D. Suelzle, Inorg. Chem., 1997, 36, 6086-6093.
[10]F. Uggeri, S. Aime, P.L. Anelli, M. Botta, M. Brocchetta, C. de Haën, G. Ermondi, M. Grandi, P. Paoli, Inorg. Chem., 1995, 34, 633-642.
[11]W. Li, S. E. Fraser e T. J. Meade, , J. Am. Chem. Soc., 1999, 121, 1413
[12]S. Aime, A. Barge, M. Botta, D. Parker, et al., Chem. Commun.,1999, 1047
[13]I. Bertini, C. Luchinat, Coord. Chem. Rev., 1996, 150, 1-295.
[14]K.M. Ward, A.H. Aletras, R.S. Balaban J. Magn. Res., 2000, 143, 79-87.
[15]S. Zhang, P. Winter, K. Wu, A.D. Sherry J. Am. Chem. Soc. 2001, 123, 1517-1518.
[16]M. Botta, Eur J Inorg Chem, 2000,3,399-407.
[17]J. Freed, Chem. Phys., 1978, 68, 4034.
[18]S.H. Koenig, R.D. Brown III, Prog. NMR Spectrosc., 1990, 22, 487.
[19]Lauffer RB, Parmelee DJ, Dunham SU, et al.,Radiology,1998, 207, 529-538.
[20]Aime S,Botta M,Fasano M,Geninatti Crich S., Terreno E., Journal of Biological Inorganic Chemistry,1996,1,312-319.
[21]Li D, Haacke EM, Dolan RP, et al., Radiology,1996,201,1088.
[22]Powell D.H., Ni Dhubhghaill O.M., Pubanz D., Helm L., Lebedev Y.S., Schlaepfer W., Merbach A.E.,J. Am. Chem. Soc.,1996, 118, 9333-9346.
[23]Aime S, Gianolio E, Terreno E, Giovenzana GB, Pagliarin R, Sisti M, Palmisano G, Botta M, Lowe MP, Parker D., Journal of Biological Inorganic Chemistry,2000,5,488-497.
[24]Stetler-Stevenson et al, Ann Rev Cell Biol, 1993,9,541.
[25]Kljin JGM et al.,Endocrine Reviews, 1992,13,3-17.
[26]
[27]Giancotti FG and Ruoslahti E.,Science,1999,285,1028-1032.
[28]Eliceiri BP, Cheresh DA.,J Clin Invest.,1999,103,1227-1230.
[29]Eliceiri BP, Cheresh DA.,Curr Opin Cell Biol.,2001,13,563-568.
[30]Gutheil JC, Campbell TN, Pierce PR, Watkins JD, Huse WD, Bodkin DJ, Cheresh DA.,Clin Cancer Res.,2000,6,3056-3061.
[31]Stary HC et Al.,Circulation,1995,92,1355-1274.
[32]Lefer DJ et Al.,Am J Physiol,1999,276 (heart Circ. Physiol 45) H1943-H1950.
[33]Minamino T et Al.,J Clin Invest.,1998,101,1643-1653.
[34]Topol EJ et Al.,Circulation,2000,101:570-580.
[35]Gerber BL et Al.,Circulation 2000,101,2734-2741.
[36]Wu KC et Al.,Circulation,1998;97:765-772.
[37]Wilke N. et Al.,Magn Reson Med,1993,29,485-497.
[38]Lombardi M. Et Sl.,J Magn Reson Imaging,1997,7,987-95.
[39] Larsson HBW et Al.,J magn Reson Imaging,1994;4:433-440.
[40]Wilke N. et Al.,J Magn Reson Med,1995,5,227-237.
[41] Lombardi ;. Et Al., J Magn Reson Imaging,1999,9,402-408.
[42]Sardanelli F. et Al.,Radiology,2000,214:808-814.
[43]Sardanelli F. et Al.,Eur Radiol,2001 (in press).

Parole Chiave

Risonanza Magnetica per Immagini; Mezzi di Contrasto; Oncologia; Placca aterosclerotica