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SCHEDA FIRB
italiano - english
Unità di Ricerca
- Azienda Ospedaliera Policlinico S.Orsola-Malpighi Bologna
Medicina Nucleare, BOLOGNA (BO) - Universita' degli Studi di BOLOGNA
MEDICINA INTERNA E GASTROENTEROLOGIA, BOLOGNA (BO) - Azienda Ospedaliera Policlinico S.Orsola-Malpighi Bologna
CRBA, BOLOGNA (BO) - Universita' degli Studi di BOLOGNA
IS?, BOLOGNA (BO) - Universita' degli Studi di BOLOGNA
IS?, BOLOGNA (BO)
FIRB simili:
- 1 - Sviluppo di metodologie innovative per l'identificazione e la sintesi di nuove molecole a scopo terapeutico: applicazioni nel campo della malattia di Alzheimer
- 2 - Sistemi di diagnostica molecolare per l'identificazione e l'analisi di determinanti genetici di rilevanza per l'agroindustria, la zootecnica e l'ambiente
- 3 - Identificazione ed analisi funzionale delle alterazioni molecolari e geniche che caratterizzano i tumori della mammella ormono-responsivi
- 4 - Caratterizzazione genetico-molecolare delle neoplasie umane: le leucemie mieloidi acute ed i sarcomi.
- 5 - Nuovi strumenti biotecnologici e post-genomici utilizzabili per la rivascolarizzazione dei tessuti nelle malattie ischemiche.
- 6 - Progettazione, sintesi e screening biologico con metodi ad alta resa di librerie combinatoriali di molecole sviluppate a partire da unità strutturali originali, per applicazioni in campo terapeutico e diagnostico
- 7 - Molecole innovative ad attività antiflogistica ed antitumorale prodotte con metodologie chimiche avanzate
- 8 - Sviluppo di microsistemi multifunzionali per analisi in diagnostica clinica e nel settore alimentare
- 9 - Modelli transgenici per malattie ad eziologia complessa
- 10 - Metodologie Innovative di Risonanza Magnetica (RM) in Patologie Tumorali e Cardiovascolari
Classificazione scientifico-disciplinare
- Area scientifico disciplinare: Scienze mediche
Classificazione brevettuale
- CHEMISTRY; METALLURGY
- ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B3/00, C25B7/00)
- PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)
- ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B3/00, C25B7/00)
- HUMAN NECESSITIES
- AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- MEDICAL OR VETERINARY SCIENCE; HYGIENE
- DIAGNOSIS; SURGERY; IDENTIFICATION (analysing biological material G01N, e.g. G01N33/48; obtaining records using waves other than optical waves, in general G03B42/00)
- AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
Classificazione geografica
- Regione: Emilia Romagna
Bibliografia
Tecnologia legata alla PETChen X, et al.(2004) Bioconjug Chem. 15:41-9.
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De A, Lewis XZ et al. (2003) Mol Ther. 7:681-91
Luker GD, et al. (2003) Cancer Res. 63:1780-8.
Liang Q, et al. (2002) Mol Ther. 6:73-82
Sun X, et al. (2001) Gene Ther.8:1572-9
Phelps ME, (2000)Proc Natl Acad Sci U S A. 97:9226-33.
Hamacher K. et al, (1986) J Nuc.Med,27:235-238
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Pascali C. et al,(1999) J. Labelled Cpd.Radiopharm.42;715-724
Ben-David I et al.,(2003) Applied Radiation and Isotopes 58; 209-217
PET legata all'oncologia
Saltz L, et al (2001). Proc Am Soc Clin Oncol; abs 7
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Hurwitz H, et al (2003). Proc Am Soc Clin Oncol; abs 3646
Hammond LA, et al (2003). Proc Am Soc Clin Oncol; abs 544
Blanke CD, , et al (2002). Proc Am Soc Clin Oncol; abs 505
Ben-David I, et al. (2003). Appl Radiat Isot; 58: 209-17
Jayson GC, et al. (2002). J Natl Cancer Inst; 94: 1484-93
McCarthy TJ, et al. (2002). J Nucl Med; 43: 117-24
Czernin J, et al. (2002). Annu Rev Med; 53:89-112
Impiego della micro-PET
Mc Neil (2003) The Scientist March 10, 31
Marx J (2003) Science 302: 1880-1882
PET legata all'obesità
Gifford AN, et al. Chem Phys Lip (2002), 121:65;
Katoch-Rouse R et al. J Med Chem (2003), 46:642;
Mathews WB et al. Nucl Med Biol (2000), 27:757-762;
Cota et al. J. Clin Invest. (2003), 112:423-431;
Cota et al. J Endocrinol Invest.(2003), 26:1041-1044;
Tataranni PA et al. Proc Nat Acad Sci(1999), 96:4569-4574;
Del Parigi A. et al. Ann. N.YAcad Sci (2002), 967,389-397;
Bingham EM et al., Diabetes (2002), 51,3384-3390;
Tataranni PA et al., Obesity Review (2003), 4: 229-238;
McCarthy TJ et al J.Pharm Exp Ther (2002), 301:878-883;
Del Parigi A et al Ann NY Acad Sci (2002), 967: 389-397;
Tataranni PA et al PNAS (1999), 96:4569-4574;
Del Parigi A et al Am J Clin Nutr (2002), 75: 1017-1022
