RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - STRUTTURA E DINAMICA DI PROTEINE REDOX: DALLA COMPLESSITA' MOLECOLARE ALLE BIOTECNOLOGIE
• 2 - Genomica strutturale di metalloproteine e delle loro interazioni funzionali
• 3 - RUOLO DELLE INTERAZIONI MOLECOLARI NELL'ACQUISIZIONE DELLA STRUTTURA FUNZIONALE DI PROTEINE MODELLO
• 4 - Amiloidi e ripiegamento di proteine: un approccio teorico-sperimentale
• 5 - Studi strutturali su proteine che legano molecole idrofobiche
• 6 - Proprieta’ strutturali e attivita’ funzionale di un complesso proteico modificante la cromatina nell’uomo
• 7 - APPROCCIO TEORICO-SPERIMENTALE AGLI STATI NON-NATIVI DELLE PROTEINE: FORMAZIONE DI FIBRILLE AMILOIDI, PROTEINE DISORDINATE E DENATURATE
• 8 - Genomica funzionale di proteine citoscheletriche: evoluzione molecolare, proprietà strutturali e adattamento molecolare nella superfamiglia delle tubuline.
• 9 - Dalle singole molecole a complessi e nanoaggregati: struttura, chiralità, reattività e teoria.
• 10 - Misfolding di proteine e formazione di amiloide: studi sulle basi molecolari della comparsa e aggregazione di conformeri tossici e sulla interazione di questi con superfici sintetiche e con bersagli cellulari e tessutali

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze chimiche
• Area scientifico disciplinare: Scienze biologiche
  • BIOCHIMICA
  • BIOLOGIA MOLECOLARE

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)
  • CRYSTAL GROWTH (separation by crystallisation in general B01D9/00)
    • SINGLE-CRYSTAL-GROWTH (by using ultra-high pressure, e.g. for the formation of diamonds B01J3/06); UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL (zone-refining of metals or alloys C22B); PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE (casting of metals, casting of other substances by the same processes or devices B22D; working of plastics B29; modifying the physical structure of metals or alloys C21D, C22F); SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE (for producing semiconductor devices or parts thereof H01L); APPARATUS THEREFOR

Classificazione geografica

• Regione: Lombardia

Bibliografia

1 - MALITO E., CODA A., BILYEU K., FRAAIJE M.W., MATTEVI A (2004). Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis. JOURNAL OF MOLECULAR BIOLOGY. vol. 341 pp. 1237-1249 ISSN: 0022-2836

2 - VAN DEN HEUVEL R.H.H., SVERGUN D.I., PETOUKHOV M.V., CODA A., CURTI B., RAVASIO S., VANONI M.A., MATTEVI A. (2003). The active conformation of glutamate synthase and its binding to ferredoxin. JOURNAL OF MOLECULAR BIOLOGY. vol. 330 pp. 113-128 ISSN: 0022-2836

3 - PEARSON AR, MOZZARELLI A, ROSSI GL (2004). Microspectrophotometry for structural enzymology. CURRENT OPINION IN STRUCTURAL BIOLOGY. vol. 14 pp. 656-662 ISSN: 0959-440X

4 - FERRARI D, DI VALENTIN M, CARBONERA D, MERLI A, CHEN Z-W, MATHEWS FS, DAVIDSON VL, ROSSI GL (2004). Electron transfer in crystals of the binary and ternary complexes of methylamine dehydrogenase with amicyanin and cytochrome c551i as detected by EPR spectroscopy. JBIC. vol. 9 (2) pp. 231-237 ISSN: 0949-8257

5 - VAN AMSTERDAM IMC, UBBINK M, EINSLE O, MESSERSCHMIDT A, MERLI A, CAVAZZINI D, ROSSI GL, CANTERS GW (2002). Dramatic modulation of electron transfer in protein complexes by crosslinking. NATURE STRUCTURAL BIOLOGY. vol. 9 pp. 48-52 ISSN: 1072-8368

6 - MOZZARELLI A, ROSSI GL (1996). Protein function in the crystal. ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE. vol. 25 pp. 343-365 ISSN: 1056-8700

7 - ROSSI GL (1992). Biological Activity in the Crystalline State. CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 2, 816-820 ISSN: 0959-440X

8 - C. BOSSA, M. ANSELMI, D. ROCCATANO, A. AMADEI, B. VALLONE, BRUNORI M., DI NOLA A. (2004). Extended molecular dynamics simulation of the Carbon Monoxide migration in sperm whale Myoglobin. BIOPHYSICAL JOURNAL. vol. 86 pp. 3855-3862 ISSN: 0006-3495

9 - COIRO V.M.,DI NOLA A., VANONI M.A., ASCHI M., CODA A., CURTI B., ROCCATANO D. (2004). Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates. PROTEIN SCIENCE. vol. 13 pp. 2979-2991 ISSN: 0961-8368

10 - DAIDONE I., AMADEI A., ROCCATANO D., DI NOLA A. Molecular dynamics simulation of protein folding by essential dynamics sampling: folding landscape of horse heart cytochrome c. Biophys. J. 85, 2865-2871 (2003)

11 - BRUNORI M., BURGEOIS. D., VALLONE B. (2004). The structural dynamics of myoglobin. JOURNAL OF STRUCTURAL BIOLOGY. vol. 147 pp. 223-234 ISSN: 1047-8477

12 - VALLONE B., NIENHAUS K., MATTHES A., BRUNORI M., NIENHAUS G.U. (2004). The structure of carbonmonoxy neuroglobin reveals a heme-slinding mechanism for control of ligand affinity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. ISSN: 0027-8424

13 – HUMMER G., SCHOTTE F., ANFINRUD P.A. (2004) Unveiling functional protein motions with picosecond x-ray crystallography and molecular dynamics simulations.
Proc. Nat.l Acad. Sc.i USA, 101: 15330-15334

14 - BRUNORI M., CUTRUZZOLA’ F., SAVINO C., TRAVAGLINI-ALLOCATELLI C., VALLONE B., GIBSON Q.H. (1999) Does picosecond protein dynamics have survival value? Trends Biochem. Sci., 24: 253-255

15 - GIACOMETTI G. (2004). The Role of PsbH Subunit in the Turnover of D1: A Rescue Mechanism from PSII photoinhibition. Photosynthesis and Post-Genomic Era, Trois-Rivieres, Canada. 25-28 August 2004 "From Biophysics to Molecular Biology, a Path in the Research of Photosystem II" In conjunction with the XIIIth International Congress on Photosysnthesis

16 - BERGANTINO E., BRUNETTA A., TOULOUPAKIS E., SEGALLA A., SZABO I., GIACOMETTI G. (2003). Role of the PSII-H subunit in photoprotection: novel aspects of D1 turnover in Synechocystis 6803. JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 278 pp. 41820-41829ISSN: 0021-9258

Parole Chiave

BIOLOGIA STRUTTURALE; CRISTALLOGRAFIA DI PROTEINE; DINAMICA STRUTTURALE; CINETICA ENZIMATICA; SPETTROSCOPIA DI PROTEINE; PROTEINE COMPLESSE; MICROSPETTROFOTOMETRIA DI CRISTALLI; BIOCRISTALLOGRAFIA