RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - IL PROCESSO INFIAMMATORIO: FISIOPATOLOGIA CELLULARE E MOLECOLARE
• 2 - Identificazione di nuovi bersagli farmacologici per il controllo di patologie infiammatorie e autoimmuni
• 3 - Identificazione di nuovi bersagli farmacologici per il controllo di patologie infiammatorie e autoimmuni
• 4 - Gli Herpesvirus nella patologia infiammatoria dell'endotelio: meccanismi molecolari e strategie terapeutiche.
• 5 - Gli Herpesvirus e i processi infiammatori dell'endotelio: meccanismi molecolari e strategie terapeutiche innovative
• 6 - Approccio integrato di biologia sistemica per la ricostruzione dei processi di segnalazione molecolari e di attivazione monocitaria/macrofagica in risposta a stimoli infiammatori in condizioni fisiologiche mediante tecnologie omiche.
• 7 - Invecchiamento cellulare e rimodellamento vascolare

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • PATOLOGIA GENERALE
  • MALATTIE DELL'APPARATO RESPIRATORIO
  • REUMATOLOGIA
  • MALATTIE INFETTIVE

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)
  • ORGANIC CHEMISTRY (such compounds as the oxides, sulfides, or oxysulfides of carbon, cyanogen, phosgene, hydrocyanic acid or salts thereof C01; products obtained from layered base-exchange silicates by ion-exchange with organic compounds such as ammonium, phosphonium or sulfonium compounds or by intercalation of organic compounds C01B33/44; macromolecular compounds C08; dyes C09; fermentation products C12; fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture C12P; production of organic compounds by electrolysis or electrophoresis C25B3/00, C25B7/00)
    • PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)

Classificazione geografica

• Regione: Veneto

Bibliografia

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2. NATHAN CF. Points of control in inflammation. Nature 2002, 420;846-852.

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4. SCAPINI P., NARDELLI B., NADALI C., CALZETTI F., PIZZOLO G., MONTECUCCO C., CASSATELLA M. (2003). G-CSF-stimulated neutrophils are a prominent source of f unctional BLyS. JOURNAL OF EXPERIMENTAL MEDICINE. vol. 197 pp. 297-302 ISSN: 0022-1007

5. CASSATELLA M. (1999). Neutrophil-derived proteins: selling cytokines by the pound. ADVANCES IN IMMUNOLOGY. vol. 73 pp. 369-509 ISSN: 0065-2776

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7. GARLANDA C, BOTTAZZI B, BASTONE A, MANTOVANI A. (2004). Pentraxins at the Crossroads Between Innate Immunity, Inflammation, Matrix Deposition and Female Fertility. ANNUAL REVIEW OF IMMUNOLOGY. vol. 23 pp. 337-366 ISSN: 0732-0582

8. MANTOVANI A., SICA A, SOZZANI S. ALLAVENA P, VECCHI A, LOCATI M. (2004). The chemokine system in diverse forms of macrophage activation and polirization. TRENDS IN IMMUNOLOGY. vol. 25 pp. 677-686 ISSN: 1471-4906

9. MANTOVANI A., SOZZANI S, LOCATI M, ALLAVENA P, SICA A. (2004). Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. TRENDS IN IMMUNOLOGY. vol. 23 pp. 549-555 ISSN: 14714906

10. GARLANDA C., HIRSCH E., BOZZA S., SALUSTRI A., DE ACETIS M., NOTA R., MACCAGNO A., RIVA F., BOTTAZZI B., PERI G., DONI A., VAGO L., BOTTO M., DE SANTIS R, CARMINATI P., SIRACUSA G., ALTRUDA F., VECCHI A., ROMANI L., MANTOVANI A. (2002). Non-redundant role of the long pentraxin PTX3 in the anti- fungal innate immune response. NATURE. vol. 420 pp. 182-6 ISSN: 0028-0836

11. PACCANI SR, TONELLO F, GHITTONI R, NATALE M, MURARO L, D'ELIOS MM, TANG WJ, MONTECUCCO C., BALDARI CT (2005). Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. JOURNAL OF EXPERIMENTAL MEDICINE. vol. 201 pp. 325 - 331 ISSN: 0022-1007

12. MONTECUCCO C., TONELLO, F., ZANOTTI G. (2004). Stop the killer: how to inhibit the anthrax lethal factor metalloprotease. TRENDS IN BIOCHEMICAL SCIENCES. vol. 29 pp. 282-285 ISSN: 0968-0004

13. MONTECUCCO C., DE BERNARD M. (2003). Immunosoppressive and Proinflammatory Activities of the VacA Toxin of Helicobacter pylori. JOURNAL OF EXPERIMENTAL MEDICINE. vol. 198 pp. 1767-1771 ISSN: 0022-1007

14. TONELLO F, SEVESO M, MARIN O, MOCK M, MONTECUCCO C. (2002). Pharmacology: screening inhibitors of anthrax lethal toxin. NATURE. vol. 418 pp. 386 ISSN: 0028-0836

15. AGOSTINI C., CALABRESE F., REA F., FACCO M., TOSONI A., LOY M., BINOTTO G., VALENTE M., TRENTIN L., SEMENZATO G. (2001). CXCR3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection. AMERICAN JOURNAL OF PATHOLOGY. vol. 158 pp. 1703-1711 ISSN: 0002-9440 IF 6.946.

16. AGOSTINI C., FACCO M., SIVIERO M., CAROLLO D., GALVAN S., CATTELAN A.M., ZAMBELLO R., TRENTIN L., SEMENZATO G. (2000). CXC chemokines IP-10 and Mig are expressed and direct migration of pulmonary CD8+/CXCR3+ T cells in the lung of patients with HIV infection and T-cell alveolitis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 162 pp. 1466-1473 ISSN: 1073-449XIF 8.876.

17. AGOSTINI C., TRENTIN L., PERIN A., FACCO M., SIVIERO M., PIAZZA F., BASSO U., SEMENZATO G. (1999). Regulation of alveolar macrophage/T cell interactions durino Th1-type sarcoid inflammatory process. AMERICAN JOURNAL OF PHYSIOLOGY. vol. 277 pp. L240-L250 ISSN: 0002-9513 IF 3.900.
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18. AGOSTINI C., CASSATELLA M.A., SANCETTA R., ZAMBELLO R., TRENTIN L., GASPERINI S., PERIN A., PIAZZA F., QIN S., LUSTER A. D., CHILOSI M., SEMENZATO G. (1998). Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. JOURNAL OF IMMUNOLOGY. vol. 161 pp. 6413-6420 ISSN: 0022-1767 IF: 6.702.

19. BOSSI F, FISCHETTI F, PELLIS V, BULLA R, FERRERO E, MOLLNES TE, REGOLI D, TEDESCO F. (2004). Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex. JOURNAL OF IMMUNOLOGY. vol. 173 pp. 6921-6927 ISSN: 0022-1767

20. PAUSA M., PELLIS V, M. CINCO, P G. GIULIANINI, G. PRESANI, S. PERTICARARI, R. MURGIA, TEDESCO F. (2003). Serum resistant strains of Borrelia Burgdorferi evade complement-mediated killing by expressing a CD59-like complement inhibitory molecule. JOURNAL OF IMMUNOLOGY. vol. 170 (6) pp. 3214-22 ISSN: 0022-1767

21. DOBRINA A., PAUSA M., FISCHETTI F., BULLA R., VECILE E., FERRERO E., MANTOVANI A., TEDESCO F. (2002). Cytolytically inactive terminal complement complex causes transendothelial migration of polymorphonuclear leukocytes in vitro and in vivo. BLOOD. vol. 99 pp. 185-192 ISSN: 0006-4971

22. AGOSTINI C., CASSATELLA M.A., SANCETTA R., ZAMBELLO R., TRENTIN L., GASPERINI S., PERIN A., PIAZZA F., QIN S., LUSTER A. D., CHILOSI M., SEMENZATO G. (1998). Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. JOURNAL OF IMMUNOLOGY. vol. 161 pp. 6413-6420 ISSN: 0022-1767 IF: 6.702.

Parole Chiave

INFIAMMAZIONE; FAGOCITI; CITOCHINE-CHEMOCHINE; COMPLEMENTO; TOSSINE BATTERICHE; PROTEINE DELLA FASE ACUTA; ESPRESSIONE GENICA