RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - Meccanismi molecolari ed effetti biologici della resistenza agli antibiotici in cocchi e bacilli Gram-positivi
• 2 - STUDIO DEI MECCANISMI MOLECOLARI DI ATTIVITA'/RESISTENZA DI SOSTANZE ANTIMICROBICHE
• 3 - Meccanismi molecolari di attività antimicrobica e di resistenza in microrganismi gram positivi
• 4 - Interazioni batterio-cellula ospite: analisi genetica e molecolare di meccanismi di virulenza di patogeni enterici di rilevanza clinica con particolare riferimento alla loro capacità di alterare a proprio vantaggio la risposta immune innata dell’ospite.
• 5 - Funghi patogeni opportunisti: meccanismi molecolari della virulenza, dell'interazione con cellule dell'ospite e nuove strategie di terapia antimicotica
• 6 - Antibiotico-resistenza, virulenza e fitness in patogeni Gram-positivi e Gram-negativi.
• 7 - Peptidi antimicrobici come modelli per lo sviluppo di agenti terapeutici con proprietà anti-infettive e di potenziamento delle difese dell'ospite
• 8 - Problemi emergenti di antibiotico-resistenza e virulenza in batteri patogeni Gram-positivi e Gram-negativi.
• 9 - Biofilm microbici come sistema dinamico in risposta allo stress ambientale. Approcci innovativi nella prevenzione e formulazione di nuove strategie terapeutiche integrate.
• 10 - Farmaco-resistenza di Mycobacterium tuberculosis: aspetti molecolari e farmaco-dinamici

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • MICROBIOLOGIA E MICROBIOLOGIA CLINICA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (bringing into special physical form A61J [N: mechanical aspects]; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; compounds per se C01, C07, C08, C12N; soap compositions C11D; micro-organisms per se C12N) [C0203]

Classificazione geografica

• Regione: Piemonte

Bibliografia

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Carlone N.A., Cuffini A.M., Tullio V. Interazione tra batteri, chemioantibiotici e fagociti: stato dell'arte. L'Igiene Moderna, 1995, 104: 293-309.

Clancy J., Petitpas J. W., Dib-Hajj F., Yuan W., Cronan M., Kamath A., Bergeron J., Retsema J. Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes. Mol. Microbiol., 1996, 22: 867-879

Cuffini, A.M., Tullio, V., Giacchino, F., Bonino, A., Mandras, N., Bianchi, N., Roana, J., Scalas, D., Bonello, F., Carlone, N.A. Improved phagocyte response by co-amoxiclav in renal transplant recipients. Transplantation, 2001, 71: 575-577.

Cuffini A.M., Tullio V., Mandras N., Roana J., Banche G., Carlone N.A. The leading role of antimicrobial agents in modulating the binomial host-microorganism. Curr. Med. Chem. Anti-infective Agents, 2004, 3: 1-13.

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Edwards M.L., Fagan P. K., Currie B. J., Sriprakash K. S.. The fibronectin-binding capacity and host cell adherence of Streptococcus pyogenes strains are discordant with each other. Microb. Infect., 2004, 6: 1156-1162.

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Furneri, P. M., Rappazzo G., Musumarra M. P., Tempera G., Roccasalva L. S.. Genetic basis of natural resistance to erythromycin in Mycoplasma hominis. J. Antimicrob. Chemother., 2000, 45:547-548.

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Giovanetti E., Montanari M.P., Mingoia M., Varaldo P.E. Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains. Antimicrob. Agents Chemother., 1999, 43: 1935-1940.

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Kang S., Lucky A.W., Pariser D., Lawrence I., Hanifin J.M. Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. J. Am. Acad. Dermatol., 2001, 44 (Suppl 1):S58-S64.

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Parole Chiave

PATOGENI RESPIRATORI; STREPTOCOCCUS PYOGENES; MACROLIDI; ANTIBIOTICO-RESISTENZA; IMMUNITÀ ASPECIFICA; CHERATINOCITI; FAGOCITOSI/KILLING INTRACELLULARE; INTERAZIONE PMN-ANTIBIOTICI-MICRORGANISMI; CITOCHINE