RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - IMMUNITA' INNATA E MALATTIA CELIACA
• 2 - COINVOLGIMENTO MULTI-ORGANO NELLA TELEANGIECTASIA EMORRAGICA EREDITARIA (HHT) O MALATTIA DI RENDU-OSLER-WEBER.
• 3 - Interazioni fra Mycobacterium Avium Paratuberculosis ed ospite nella patogenesi della malattia di Crohn
• 4 - Ruolo delle adipochine, citochine infiammatorie e linfociti T regolatori nel determinismo dell’aterosclerosi accelerata e della sindrome metabolica in corso di lupus eritematoso sistemico.
• 5 - FATTORI PREDISPONENTI L'INFIAMMAZIONE CRONICA DELL'INTESTINO:BATTERI,VIRUS,PERMEABILITA' INTESTINALE E PREDISPOSIZIONE GENETICA
• 6 - Geni dell'angiogenesi indotti da ipossia: fattori di suscettibilità nella Sclerosi Laterale Amiotrofica ?
• 7 - ANALISI MOLECOLARE E FARMACOLOGICA DI MEDIATORI E TRASPORTATORI COINVOLTI IN PATOLOGIE FUNZIONALI E INFIAMMATORIE INTESTINALI
• 8 - PROGRESSIONE DA MGUS A MIELOMA MULTIPLO: PATOGENESI MOLECOLARE, IDENTIFICAZIONE DI POTENZIALI MARCATORI PROGNOSTICI E SVILUPPO PRECLINICO DI RAZIONALI APPROCCI CHEMIOPREVENTIVI
• 9 - Autoimmunita' e intestino
• 10 - Studio dei meccanismi etiopatogenetici nel pemfigo

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • ANATOMIA PATOLOGICA
  • MEDICINA INTERNA
  • MALATTIE ODONTOSTOMATOLOGICHE

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY (installation for fermenting manure A01C3/02; preservation of living parts of humans or animals A01N1/02; physical or chemical apparatus in general B01; malting or mashing apparatus C12C1/00; brewing apparatus C12C13/00; fermentation apparatus for wine C12G; apparatus for preparing vinegar C12J1/10)
    • MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (bringing into special physical form A61J [N: mechanical aspects]; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; compounds per se C01, C07, C08, C12N; soap compositions C11D; micro-organisms per se C12N) [C0203]

Classificazione geografica

• Regione: Sicilia

Bibliografia

BIBLIOGRAFIA
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2) Farrell R et al. Current concepts: celiac disease. N Engl J Med 2002; 346: 180-8.
3) Catassi C et al. The celiac iceberg in Italy: a multicentre antigliadin antibodies screening for celiac disease in school-age subjects. Acta Pediatr Suppl 1996; 412:29-35.
4) Kolho KI et al. Undiagnosed celiac disease is common in Finnish adults. Scand J Gastroenterol 1998; 33: 1280-3.
5) Carlsson AK et al. Serological screening for celiac disease in healthy 2.5-year-old children in Sweden. Pediatrics 2001; 107: 42-5.
6) Cottone M et al. Mortality and causes of death in celiac disease in a Mediterranean area.
Dig Dis Sci. 1999 Dec;44(12):2538-41
7) Catassi C. et al. Risk of non-Hodgkin lymphoma in celiac disease.
JAMA2002;287:1413-9.
8) Corrao G et al. Mortality in patients with coeliac disease and their relatives: a cohort study.
Lancet. 2001; 358: 356-61.
9) Green PHR. Et al. Celiac disease. Lancet 2003; 362: 383-91.
10) Holmes GKT et al. Malignancy in coeliac disease – effect of a gluten-free diet. Gut 1989; 30: 333-8.
11) Logan RFA. Problems and pitfalls in epidemiological studies of coeliac disease. Dyn Nutr Res 1992; 2:14-24
12) Rostami K et al. Sensitivity of antiendomysium and antigliadin antibodies in untreated celiac disease: disappointing in clinical practice. Am J Gastroenterol 1999;94:888-894.
13) Baldas V, Tommasini A, Trevisiol C, et al. Development of a novel rapid non-invasive screening test for coeliac disease. Gut 2000;47:628-631.
14) Dieterich W, Laag E, Schopper H, et al. Autoantibodies to tissue transglutaminase as predictors of celiac disease. Gastroenterology 1998;115:1317-1321.
15) Sulkanen S, Halttunen T, Laurila K, et al. Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease. Gastroenterology 1998;115:1322-1328.
16) Williams AJ, Norcross AJ, Lock RJ, Unsworth DJ, Gale EA, Bingley PJ: The high prevalence of autoantibodies to tissue transglutaminase in first-degree relatives of patients with type 1 diabetes is not associated with islet autoimmunity. Diabetes Care. 2001;24:504-9.
17) Picarelli A, Di Tola M, Sabbatella L, Vetrano S, Anania MC, Spadaro A, Sorgi ML, Taccari E: Anti-tissue transglutaminase antibodies in arthritic patients: a disease-specific finding?
Clin Chem. 2003; 49:2091-4.
18) Carroccio A, Soresi M, Di Prima L, Montalto G. Screening for celiac disease in patients with chronic liver disease. Gastroenterology 2003; 125: 1289-90.
19) Carroccio A, Vitale G, Di Prima L. Comparison of anti-transglutaminase ELISAs and anti-endomysial antibody assay in the diagnosis of celiac disease: a prospective study. Clin Chem 2002; 48: 1546-50.
20) Carroccio A, Iacono G, D’Amico D, et al. Production of antiendomysial antibodies in cultured duodenal mucosa: usefulness in coeliac disease diagnosis. Scand J Gastroenterol 2002; 37: 32-8.
21) Picarelli A, Maiuri L, Frate A, Greco M, Auricchio S, Londei M. Production of antiendomysial antibodies after in vitro gliadin challenge of small intestine biopsy samples from patients with coeliac disease. Lancet 1996; 348: 1065-7.
22) Picarelli A., Di Tola M., Sabbatella L., Anania M.C., Di Cello T., Greco R., Silano M., De Vincenzi M.: 31-43 amino acid sequence of the -gliadin induces anti-endomysial antibody production during in vitro challenge. Scand. J. Gastroenterol. 1999; 34: 1099-1102
23) Walker-Smith JA, Guandalini S, Schmitz J, Shmerling DH, Visakorpi JK. Revised criteria for diagnosis of coeliac disease. Arch Dis Child 1990; 65: 909-11.
24) Vogelsang H., Schwarzenhofer M., Granditsch G., Oberhuber G.: In vitro production of endomysial antibodies in cultured duodenal mucosa from patients with celiac disease. Am. J. Gastroenterol. 1999; 94: 1057-61.
25) Del Rosario MA et al. Further studies of anti-endomysium and anti-gliadin antibodies in patients with suspected celiac disease. J Ped. Gastroenterol. Nutr. 1998; 27:195-7.
26) Schuppan D. Current concepts of celiac disease pathogenesis. Gastroenterology 2000; 119: 234-42.
27) Wang W et al. Human zonulin: a potential modulator of intestinal tight junctions. J Cell Sci 2000; 113: 4435-40
28) Lahat N et al. Cytokine profile in coeliac disease. Scand J Immunol 1999;49:441-6.
29) Juuti-Uusitalo K et al. CDNA microarray analysis of gene expression in coeliac disease jejunal biopsy samples. J. Of Autoimmunity 2004; 22: 249-65.
30) Aine L et al. Dental enamel defects in coeliac disease. J oral Pathol med 1990; 19:241-5
31) Lahteenoja H et al. Oral mucosa changes in coeliac patients on a gluten-free diet. Eur J Oral Sci 1998; 105: 899-906.
32) Lahteenoja, H et al. Local challenge on oral mucosa with an alpha-gliadin related synthetic peptide in patients with celiac disease. Am J Gastroenterol, 2000. 95(10): p. 2880-7.
33) Lahteenoja, H et al. Increased T-cell subsets of oral mucosa: a late immune response in patients with tretaed coeliac disease ? Scand J Immunol 2000; 52:602-8.
34) Lahteenoja, H et al. Local challenge of oral mucosa with gliadin in patients with coeliac disease. Clin Exp Immunol. 2000; 120: 38-45.

Parole Chiave

MALATTIA CELIACA; MUCOSA ORALE; ANTICORPI ANTI-ENDOMISIO; ESPRESSIONE GENICA; COLTURE PRIMARIE DI TESSUTO; BIOPSIA ORALE