RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - Apoptosi ed Infezioni virali.
• 2 - RUOLO DEL VIRUS HERPES SIMPLEX-1 NELL'ATTIVAZIONE DI PATHWAY INTRACELLULARI COINVOLTI NELLA NEURODEGENERAZIONE: POSSIBILI IMPLICAZIONI NELLA PATOGENESI DELLA MALATTIA DI ALZHEIMER
• 3 - Infezioni virali persistenti, latenti e croniche da virus a DNA e ad RNA: studio dei meccanismi di regolazione genica e della risposta immune.
• 4 - Basi molecolari della penetrazione e della risposta dell'ospite alla infezione con herpesvirus umani
• 5 - RUOLO DELLE INFEZIONI DA HERPES SIMPLEX VIRUS -1 NELLA PATOGENESI DELLA MALATTIA DI ALZHEIMER
• 6 - Ruolo di fattori virali e cellulari nelle interazioni tra virus di Epstein-Barr e cellula ospite
• 7 - Genomica funzionale di Bovine herpesvirus type 4 (BoHV-4) sull'infezione/transduzione del sistema nervoso centrale del topo in vitro ed in vivo
• 8 - BERSAGLI MOLECOLARI PER NUOVE TERAPIE ANTINEOPLASTICHE ATTRAVERSO LO STUDIO DI PROTEINE-SEGNALE CELLULARI E VIRALI E DI INIBITORI SPECIFICI
• 9 - Fattori di virulenza e di resistenza nella patogenesi delle infezioni retrovirali
• 10 - Un approccio biomolecolare per la patologia HHV8-associata e la sua possibile trasformazione neoplastica:

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • MICROBIOLOGIA E MICROBIOLOGIA CLINICA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)

Classificazione geografica

• Regione: Lazio

Bibliografia

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2. Amini S, Mameli G, Del Valle L, Skowronska A, Reiss K, Gelman BB, White MK, Khalili K, Sawaya BE. 2005. p73 Interacts with human immunodeficiency virus type 1 Tat in astrocytic cells and prevents its acetylation on lysine 28. Mol Cell Biol. 25:8126-8138.
3. Badley, A.D., Pilon, A.A., Landay, A., and Lynch, D.H.. 2000. Mechanisms of HIV-associated lymphocyte apoptosis. Blood. 96:2951-2964.
4. Barber, G.N. 2001. Host defense, viruses and apoptosis. Cell Death Differ. 8:113-126.
5. Benedict, C.A., Norris, P.S. and Ware, C.F. 2002. To kill or be killed: viral evasion of apoptosis. Nat. Immunol. 3: 1013-1018.
6. Borner, C. 2003. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. immunol. 39:615-647.
7. Boya, P., Roumier, T., Andreau, K., Gonzales-Polo, R., Zamzami, N., Castedo, M. and Kroemer, G. 2003. Mitochondrion-targeted apoptosis regulators of viral origin. Biochem.Biophysic.Res.Commun. 304: 575-581.
8. Brenner, C., and Kroemer, G. 2000. Apoptosis. Mitochondria - the death signal integrators. Science 289: 1150-1151.
9. Castedo, M., Ferri, K.F., Blanco, J., Roumier, T., Larochette, N., Barretina, J., Amendola, A., Nardacci, R., Metivier, D., Este, J.A., Piacentini, M., and Kroemer, G. 2001. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosisinvolves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.J Exp Med. 194:1097-1110.
10. Chen, W., Calvo, P.A., Malide, D., Gibbs, J., Schubert, U., Bacik, I., Basta, S., O'Neill, R., Schickli, J., Palese P., Henklein, P.,Bennink, J.R., and Yewdell, J.W. 2001. A novel influenza A virus mitochondrial protein that induces cell death. Nat. Med. 7:
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11. Cory, S., D.C.S. Huang, and J.M. Adams. 2003. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene. 22:8590-8607.
12. De Laurenzi, V., Costanzo, A., Barcaroli, D., Terrinoni, A., Falco, M., Annicchiarico-Petruzzelli, M., Levrero, M. and Melino, G. 1998. Two new p73 splice variants, gamma and delta, with different transcriptional activity. J Exp Med 188: 1763-1768.
13. Dobbelstein, M., and Roth, J. 1998. The large T antigen of simian virus 40 binds and inactivates p53 but not p73. J. Gen Virol.79: 3079-3083.
14. Du, C., Fang, M., Li, Y., Li, L., Wang, X. 2000. Smac, a mitochondrial protein that promotes cytochrome-c dependent caspaseactivation by eliminating IAP inhibition. Cell 101: 33-42.
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29. Marchenko, N.D., Zaika, A., and Moll, U.M. 2000. Death signal-induced localisation of p53 to mitochondria. A potential role in apoptosis signalling. J. Biol. Chem 275: 16202-16212.
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32. Nencioni, L., Iuvara, A., Aquilano, K., Circolo, M.R., Cozzolino, F., Rotilio, G., Garaci, E. and Palamara, A.T. 2003. Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J. 17: 758-760.
33. Polster, B.M., J. Pevsner, and J.M. Hardwick. 2004. Viral Bcl-2 homologs and their role in virus replication and associated diseases. Bioch. Biophys. Acta. 1644:211-227.
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35. Steengenga, W.T., Shvarts, A., Riteco, N., Bos, J.L., and Jochemsen, A.G. 1999. Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins. Mol. Cell. Biol. 19: 3885-3894.
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Parole Chiave

MICROBIOLOGIA, APOPTOSI, VIRUS, INFEZIONE