RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - Ruolo dei polimorfismi dei geni GH1, IGF1 e IGFBP3 coinvolti nella patogenesi della bassa statura da deficit di GH e idiopatica.
• 2 - Implicazioni di mutazioni del gene gamma, responsabili di fenotipi umani SCID-X1, sull'apparato di signaling del recettore per il GH
• 3 - Meccanismi di controllo dell’eritropoiesi e policitemie congenite e familiari: ruolo delle vie di risposta alla pressione di ossigeno
• 4 - Neurogenesi ed accrescimento neuritico: segnali extracellulari e meccanismi di regolazione comuni per differenti processi di crescita
• 5 - Il colangiocarcinoma: approccio terapeutico basato su nuove acquisizioni di biologia cellulare e molecolare.
• 6 - Interruttori molecolari che controllano l'omeostasi dei sistemi metabolici e vascolari: dai modulatori del RNA a quelli della trasmissione del segnale
• 7 - Studio sulle basi molecolari della "Compensatory growth" in una specie ittica di rilevante interesse per l'acquacoltura mediterranea, finalizzato al controllo della qualità del prodotto.
• 8 - PRODUZIONE E CATABOLISMO DELLA BETA-AMILOIDE IN PAZIENTI CON MALATTIA DI ALZHEIMER E MILD COGNITIVE IMPAIRMENT: STUDI IN VITRO E MARKERS EX VIVO
• 9 - PCSK9 e colesterolo LDL: Studi genetici per la valutazione di un nuovo target farmacologico nelle dislipidemie.
• 10 - PEROSSIDAZIONE LIPIDICA, ATTIVAZIONE PIASTRINICA ED INFIAMMAZIONE ASSOCIATI A RIDOTTI LIVELLI DI LIPOPROTEINE AD ALTA DENSITA' (HDL)

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • GENETICA MEDICA
  • PATOLOGIA CLINICA
  • ENDOCRINOLOGIA
  • PEDIATRIA GENERALE E SPECIALISTICA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (bringing into special physical form A61J [N: mechanical aspects]; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; compounds per se C01, C07, C08, C12N; soap compositions C11D; micro-organisms per se C12N) [C0203]

Classificazione geografica

• Regione: Puglia

Bibliografia

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-Rosenfeld RG, Buckway CK 2001 Growth hormone insensitivity syndromes: lessons learned and opportunities missed. Horm Res 55(Suppl 2):36 –39.
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-Collett-Solberg PF, Rajah R, Weinzimer SA, Cohen P 1999 The impact of IGF-binding proteins and IGFBP proteases on tissue growth, in: F.E. Johnston, P.B. Eveleth, B. Zemel (Eds.), Human
Growth in Context, Smith-Gordon, London.
-de Zegher F, Kimpen J, Raus J, Vanderschueren-Lodeweyckx M 1990 Hypersomatotropism in the dysmature infant at term and preterm birth. Biol Neonate. 58(4):188-91.
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-Giudice LC, de Zegher F, Gargosky SE, et al. 1995 Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocrinol Metab. 80:1548 –1555.
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Parole Chiave

MEDIATORI DEL SEGNALE DI CRESCITA, PICCOLO PER L'ETÀ GESTAZIONALE, BASSA STATURA IDIOPATICA, PTPN11/SHP2, IGF-I, IGFBP3, GENE SOCS2, GENE SHOX, GENE NPR2