RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - PROCESSI CATALITICI INNOVATIVI PER L'OSSIDAZIONE E RIDUZIONE SELETTIVA DEL GLICEROLO IN ACQUA: STUDIO DI MECCANISMI E CINETICHE DI REAZIONE PER L'OTTIMIZZAZIONE DEL PROCESSO
• 2 - Materiali microstrutturati prodotti mediante processi innovativi assistiti da fluidi supercritici
• 3 - Sviluppo di materiali polimerici per applicazioni biomediche mediante tecnologie innovative sostenibili
• 4 - Analisi sperimentale, modellazione e simulazione di reattori slurry per l'abbattimento di inquinanti
• 5 - UN APPROCCIO INTEGRATO ALLA SINTESI, CARATTERIZZAZIONE E FUNZIONE DI BIOPOLIMERI EUMELANICI DERIVANTI DA 5,6-DIIDROSSIINDOLI E LORO MISCELAZIONE CON POLIMERI CONVENZIONALI E COMPOSITI
• 6 - Studi su meccanismi chiave del comportamento di letti fluidizzati e loro implementazione in strumenti di simulazione numerica per applicazioni nell'industria di processo.
• 7 - Complessi porfirinici autoorganizzati su scala nanoscopica: proprietà e applicazioni tecnologiche
• 8 - Ottimizzazione delle proprietà funzionali di imballaggi in poliestere mediante il controllo morfologico, nanofiller e rivestimenti nanorinforzati
• 9 - Attivazione ossidativa catalitica e fotocatalitica per la sintesi organica
• 10 - Modellazione avanzata e validazione sperimentale di dettaglio della fluidodinamica di reattori gas-liquido agitati per processi chimici e biotecnologici

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Ingegneria industriale e dell'informazione
  • CHIMICA FISICA APPLICATA
  • PRINCIPI DI INGEGNERIA CHIMICA
  • IMPIANTI CHIMICI
  • TEORIA DELLO SVILUPPO DEI PROCESSI CHIMICI

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON (manufacture or treatment of artificial threads, fibres, bristles or ribbons D01 [C9410]
    • WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G (mechanical aspects B29; layered products, manufacture thereof B32B; treatment of macromolecular material specially adapted to enhance its filling properties in mortars, concrete or artificial stone C04B16/04, C04B18/20, C04B20/00; treatment of texiles D06) [C9410]
  • PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION (cracking to hydrogen or synthesis gas C01B; cracking or pyrolysis of hydrocarbon gases to individual hydrocarbons or mixtures thereof of definite or specific constitution C07C; cracking to cokes C10B); RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES (inhibiting corrosion or incrustation in general C23F) [C9506]
  • TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE (settling tanks, filtering, e.g. sand filters or screening devices, B01D)
    • TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE (separation in general B01D; special arrangements on waterborne vessels of installations for treating water, waste water or sewage, e.g. for producing fresh water, B63J; adding materials to water to prevent corrosion C23F; treating radioactively-contaminated liquids G21F9/04; regeneration of reactants for recirculation into processes, see the relevant places for the processes)
• HUMAN NECESSITIES
  • MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES (bringing into special physical form A61J [N: mechanical aspects]; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; compounds per se C01, C07, C08, C12N; soap compositions C11D; micro-organisms per se C12N) [C0203]

Classificazione geografica

• Regione: Sicilia

Bibliografia

Alcamo R:, Micale G., Grisafi F., Brucato A. and Ciofalo M., 2005, Large-eddy limulation of turbulent flow in an umbaffled stirred tank driven by a Rushton turbine, Chemical Engineering Science, 60 , pp. 2303 -2316, 2005

Baldyga, J., Bourne, 1999, Turbulent mixing and chemical reaction, New York, Wiley .

Baldyga, J., Orciuch W., 2001, Barium sulphate precipitation in a pipe - An experimental study and CFD modelling, Chemical Engineering Science, 56, pp. 2435-2444 .

Baldyga J, Makowski L , 2004, CFD modelling of mixing effects on the course of parallel chemical reactions carried out in a stirred tank, Chem.Eng. Technol., 27 (3): 225-231

Brannon-Peppas L. Blanchette JO., 2004.Nanoparticle and targeted systems for cancer therapy. Advanced Drug Delivery Reviews, 56:1649-1659

Briancon, S., Fessi, H., Le conte, F., Lieto, J., 1999, Study and scale-up of a nanoprecipitation process, Proc. 14th Int. Symp. Ind .Cryst., I.Chem.E., Cambridge .

Cerbelli, S., Giusti, A. and Soldati, A. 2001. ADE approach to predicting particle dispersion in wall bounded turbulent flows. J .Multiphase Flow. 27: 1861-1879 .

Ciofalo M., A.Brucato, F. Grisafi and N. Torraca, 1996, Turbulent flow in closed and free-surface unbaffled tanks stirred by radial impellers, Chemical Engineering Science, 51, pp.3357-3573

Couvreur P, Dubernet C, Puisieux F. 1995. Controlled drug delivery with nanoparticles: current possibilities and future trends. Eur J Pharm Biopharm 41:2-13 .

Couvreur P, Kante B, Roland M, Guiot P, Baudhuin P, Speiser P. 1979. Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: Preparation, morphological and sorptive properties. J Pharm Pharmacol 31:331-332 .

Das P.K., Legrand J., Morancais P. & Carnelle G. (2005) Drop breakage model in static mixers at low and intermediate Reynolds number, Chem. Eng. Sci. 60, 231-238 .

Dirksen, J.A., Ring. T.A., 1991, Fundamentals of crystallization. Kinetic effects on particle size distributions and morphology, Chem .Eng. Sci., 46, 2389 .

Fessi, H., Puisieux, F., Devissaguet, J. Ph., Ammoury, N., and Benita, S., 1989, Nanocapsule formation by interfacial polymer deposition following solvent-displacement, International Journal of Pharmaceutics, 55, pp. R1-R4 .

Fox, R.O., 1998, On the relationship between Lagrangian micromixing models and computational fluid dynamics, Chem. Eng. Proc., 37, 521-535

Fradette, L., Li, H., Choplin, L., Tanguy, P.A., (1998). 3D finite element simulation of fluid flow through a static mixer. Computers Chemical Engineering, 22, S759-S761

Garin-Chesa P, Campbell I, Saigo P, Lewis J, Old L, Rettig W. 1993. Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am J Path 142:557-567 .

Horn, D. and Rieger, J., 2001, Organic nanoparticles in the aqueous phase - theory, experiments and use, Angewandte Chemie-International Edition, 40, 4331-4361 .

Hulburt, H.M., Katz, S., 1964, Some problems in particle technology, Chemical Engineering Science, 19, pp. 555-574 .
Johnson, B.K., 2003, Flash Nanoprecipitation of Organic Actives via Confined Micromixing and Block Copolymer Stabilisation, Ph.D. Thesis, Princeton University .

Mahajan, A.H., Kirwan, D.J., 1996, Micromixing effects in a two-impinging-jets precipitator, AIChE Journal, 42, pp. 1801-1814 .

Marchioli, C., Giusti, A., Salvetti, M.V. and Soldati, A. 2003 Direct Numerical Simulation of Particle Wall Transfer and Deposition in Upward Turbulent Pipe Flow, Int. J. Multiphase Flow. 29: 1017-1038 .

Marchisio, D.L., Barresi, A.A., and Fox, R.O., 2001a, Simulation of Turbulent Precipitation in a Semi-batch Taylor-Couette Reactor Using CFD, AIChE Journal, 47, pp. 664-676 .

Marchisio, D.L., Fox, R. O., Barresi, A.A., and Baldi, G., 2001b, On the comparison between Presumed and Full PDF methods for turbulent precipitation, Industrial Engineering Chemistry Research, 40, pp. 5132-5139 .

Marchisio, D.L., Barresi, A.A., 2003, CFD simulation of mixing and reaction: the relevance of the micro-mixing model, Chemical Engineering Science, 58, pp. 3579-3587 .

Marchisio, F.L., Pikturna, J.T., Fox, R.O., Vigil, D.R., and Barresi, A.A., 2003, Quadrature method of moments for population balances, AIChE Journal, 49, pp. 1266-1279 .

Marchisio, D.L., Fox, R.O., 2005, Solution of population balance equations using the direct quadrature method of moments, Journal of Aerosol Science, 36, pp. 43-73 .

Maxey, M.R., and Riley, J.J. 1983. Equation of Motion for a Small Rigid Sphere in a Nonuniform Flow. Phys. Fluids. 26: 883-889 .

McGraw, R., 1997, Description of aerosol dynamics by the quadrature method of moments. Aerosol Science & Technology, 27, pp .
255-267 .

Moin, P., Mahesh, K., 1998, Direct numerical simulation: a tool in turbulence research, Ann. Rev. Fluid Mech., 30, 539-578 .

Rauline, D., Tanguy, P.A., Le Blevec J-M, Bousquet, J., (1998). Numerical investigations of the performance of several static mixer . Canadian Journal of Chemical Engineering 76, 527-535 .

Rousseaux, J. M., Falk, L., Muhr, H., & Plasari, E. (1999). Micromixing efficiency of a novel sliding-surface mixing device . A.I.Ch.E.Journal, 45(10), 2203}2213 .

Rousseaux, J. M., Falk, L., Muhr, H., & Plasari, E. (2001). CFD simulation of precipitation in the sliding surface mixing device . Chem. Eng. Science, 56, 1677-1685 .

Sbrizzai, F., Faraldi, P. and Soldati, A. 2005. Appraisal of 3D numerical simulation for sub-micron particle deposition in a micro-porous ceramic filter. Chem. Eng. Sci. 60 .

Sbrizzai, F., Verzicco, R., Pidria, M. and Soldati, A. 2004. Mechanisms for Selective Radial Dispersion of Microparticles in the Transitional Region of a Confined Turbulent Round Jet. Int. J. Multiphase Flow. 30: 1389-1417 .

Stella, B., Arpicco, S., Peracchia, M.T., Desmaele, D., Hoebeke, J., Renoir, M., D'Angelo, J., Cattel, L., Couvreur., P., 2000. Design of folic acid-conjugated nanoparticles for drug targeting J. Pharm. Sci., 89, 1452-1464 .

Streiff F.A:, Jaffer S. & Schneider G. (1999) The design and application of static mixer technology. 3rd Int. Symp. on Mixing in Industrial Processes. Osaka (Japan) 107-114 .

Sudimack J, Lee RJ. 2000. Targeted drug delivery via the folate receptor. Adv Drug Del Rev 41:147-162 .
Texter, J., 2001, Precipitation and condensation of organic particles, Journal of Dispersion Science and Technology, 22, pp . 499-527 .

Thioune, O., Fessi, H., Devissaguet, J.P., and Puisieux, F., 1997, Preparation of pseudolatex by nanoprecipitation: influence of the solvent nature on intrinsic viscosity and interaction constant, International Journal of Pharmaceutics, 146, pp. 233-238 .

Vanni, M., 2000, Approximate Population Balance Equations for Aggregation-Breakage Processes, Journal of Colloid and Interface Science, 221, pp. 143-160 .

Verdun C., Brasseur F., Vranckx H., Couvreur P. and Roland M. 1990 Tissue distribution of doxorubicin associated with polyisohexyl-cyanoacrylate nanoparticles. Cancer Chemother. Pharmacol. 26: 13-18 Verzicco, R., Orlandi, P., 1996. A finite-difference scheme for the three-dimensional incompressible flows in cylindrical coordinates . J. Comp. Phys. 123: 402 .

Wang S, Low PS. 1998. Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells. J Control Rel 53:39-48.

Parole Chiave

NANOPARTICELLE, PRECIPITAZIONE, COLLAUDO E SVILUPPO DI PRECIPITATORI, MODELLAZIONE, FLUIDODINAMICA COMPUTAZIONALE, MISCELAZIONE, TURBOLENZA, BILANCIO DI POPOLAZIONE, PRODUZIONE DI FARMACI